Vajrayogini, is a representation of complete Buddhahood in female form, whose practices are associated with the Chakrasamvara Cycle of Anuttarayoga Tantra.
This painting is showing Vajrayogi with 21 tara and Je Tsongkhapa.
http://buddhanature.com/buddha/vajrayogini.html

Artist: Dechen Lama

Size: 35.5” x 26.5″